A Substitution That Changes One of the First Two Bases

A substitution that changes one of the first two bases in a codon (e.g., AGT) is called a _______ mutation and will ______.

A) synonymous mutation; not change the resulting amino acid
B) nonsynonymous mutation; not change the resulting amino acid
C) nonsynonymous mutation; change the resulting amino acid
D) synonymous mutation; change the resulting amino acid
E) frameshift mutation; change the resulting amino acid