How is estradiol recognized by the estrogen receptor?
A) The molecular weight is recognized.
B) The atom types in the ligands are recognized by the receptors.
C) Single bonds, double bonds, and triple bonds are recognized by receptors.
D) Receptors recognize ligands by shape only.
E) Ligands are recognized by shape and intermolecular forces of attraction.

Question

Quizplus · Accepted Answer

Estradiol, like other ligands, is recognized by its receptor through a combination of its three-dimensional shape and the intermolecular forces of attraction such as hydrogen bonds, hydrophobic interactions, and van der Waals forces. These factors together determine the specificity and strength of the ligand-receptor interaction.

How Is Estradiol Recognized by the Estrogen Receptor