You isolate a new bacterium from soil with a revolutionary new culture technique.You are interested in sequencing the genome of this organism using the whole-genome,or shotgun,sequencing approach.Of the following choices,what would be the best way to prepare the genomic DNA for sequencing?

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Using multiple restriction enzymes like EcoRI, BamHI, and HpaI will create a variety of fragment sizes, which is beneficial for shotgun sequencing as it allows for better coverage and assembly of the genome.

You Isolate a New Bacterium from Soil with a Revolutionary