The iron-response element (IRE)is a(n)
A)insulator element that binds IRE-binding protein in the absence of iron.
B)transcriptional promoter that directly binds iron to prevent transcription of nearby genes.
C)long noncoding RNA that binds iron and regulates transcription of multiple genes.
D)sequence in the 5ʹ untranslated region of mRNA that forms a hairpin loop,preventing translation of the mRNA by binding to IRE-binding protein in the absence of iron.
E)example of a prokaryotic riboswitch that causes early termination of transcription in the presence of iron.

Question

Quizplus · Accepted Answer

The iron-response element (IRE) is a sequence found in the 5ʹ untranslated region of mRNA. It forms a hairpin loop structure that can bind to the IRE-binding protein (IRP) when iron levels are low, preventing the translation of the mRNA. This mechanism allows cells to regulate the synthesis of proteins involved in iron metabolism in response to iron availability.

The Iron-Response Element (IRE)is A(n)