The single-celled yeast, Saccharomyces cerevisiae, was used to construct the first eukaryotic artificial chromosome.This was a significant achievement because A)yeast centromeres are identical to human centromeres. B)it defined chromosomal regions that serve as centromeres and origins of replication in yeast. C)it revealed the rate of DNA replication in yeast. D)it demonstrated that some yeast genes are not essential. E)it defined the chromosomal region with the TRP⁺ gene for tryptophan synthesis in yeast.

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This achievement was significant because it helped define chromosomal regions that serve as centromeres and origins of replication in yeast, which are essential for chromosome segregation and DNA replication, respectively.

The Single-Celled Yeast, Saccharomyces Cerevisiae, Was Used to Construct the First