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Allele-Specific Oligonucleotides (ASO)for the Normal and Disease Alleles of a Gene

Question 1

Multiple Choice

Allele-specific oligonucleotides (ASO) for the normal and disease alleles of a gene are in one section of a microarray.The disease is a recessive trait.If a probe made from an individual's genomic DNA hybridizes with both ASOs, what can be inferred about the individual?


A) The individual has two normal alleles.
B) The individual has the disease.
C) 50% of the individual's children are expected to be carriers.
D) One of the individual's parents has the disease.

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