Many cancers have a mutation that changes a valine to a glutamic acid in the RAF kinase protein which phosphorylates proteins that promote cell division.This mutant protein is a constitutively active kinase.What type of allele is this mutant allele?
A)hypomorphic allele
B)hypermorphic allele
C)null allele
D)antimorphic allele

Question

Quizplus · Accepted Answer

The mutant allele described is a hypermorphic allele because it results in a protein (RAF kinase) that is constitutively active, meaning it has increased or enhanced function compared to the wild-type allele. This leads to increased phosphorylation of proteins that promote cell division, contributing to cancer development.

Many Cancers Have a Mutation That Changes a Valine to a Glutamic