Which of the following mutant alleles is most likely to be dominant to the wild-type allele?
A)a silent mutation
B)a premature stop codon that results in a partial loss of protein function
C)a missense mutation that increases enzyme activity
D)a promoter mutation that reduces gene transcription

Question

Quizplus · Accepted Answer

A missense mutation that increases enzyme activity can result in a gain-of-function mutation, which is often dominant because the mutant protein with higher activity can overshadow the normal function of the wild-type allele.

Which of the Following Mutant Alleles Is Most Likely to Be