What is the correct order of these events in recombination that is resolved by the crossover pathway? 1.Double-strand break formation
2.Strand invasion
3.Resection
4.Resolution of the double Holliday junction
5.Branch migration
6.Formation of a double Holliday junction
A)6, 1, 2, 5, 3, 4
B)1, 2, 5, 3, 6, 4
C)6, 4, 1, 2, 5, 3
D)1, 3, 2, 6, 5, 4
E)1, 2, 3, 5, 6, 4

Question

Quizplus · Accepted Answer

The correct order starts with the formation of a double-strand break, followed by resection (trimming of the DNA ends), strand invasion (where one strand invades the homologous DNA sequence), formation of a double Holliday junction (a crossover intermediate), branch migration (which extends the region of heteroduplex DNA), and finally, resolution of the double Holliday junction, leading to crossover or non-crossover products.

What Is the Correct Order of These Events in Recombination