If an amino acid has one carboxyl group and one amino group, and the pKa's are 2.4 and 9.8 respectively, what is its isoelectric point?

Question

Quizplus · Accepted Answer

The isoelectric point (pI) of an amino acid is calculated as the average of the pKa values of the ionizable groups in the zwitterion form, which in this case are the carboxyl group (pKa = 2.4) and the amino group (pKa = 9.8). Therefore, pI = (2.4 + 9.8) / 2 = 6.1.

If an Amino Acid Has One Carboxyl Group and One