Circulating tumor cells in blood must be

Question

Quizplus · Accepted Answer

Circulating tumor cells (CTCs) are rare cells that are shed from tumors and can be found in the bloodstream. They are typically isolated using a combination of antibodies that target specific cell surface markers. In this case, CTCs would be isolated using anti-EpCAM (epithelial cell adhesion molecule), which is expressed on the surface of most epithelial tumors. The cells would then be stained with anti-cytokeratins, which are intermediate filaments that are expressed in epithelial cells. Finally, the cells would be stained with anti-CD45, which is a leukocyte common antigen that is not expressed on CTCs.

Circulating Tumor Cells in Blood Must Be