Which of the following would be the result of a mutation that inactivates cyclin-E?

Name: Which of the following would be the result of a mutation that inactivates cyclin-E?
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Question

Quizplus · Accepted Answer

Cyclin-E is crucial for the transition from the G1 phase to the S phase of the cell cycle. It helps in the activation of E2F, a transcription factor necessary for DNA synthesis. If cyclin-E is inactivated, E2F cannot bind to DNA, preventing the transcription of genes required for S phase entry.

Which of the Following Would Be the Result of a Mutation