Mutations in which of the following regions upstream of the RNA coding sequence are LEAST likely to affect the transcription of a gene?
A) -10 consensus sequence within the promoter region
B) -35 consensus sequence within the promoter region
C) the region between -10 and -35 consensus sequences
D) the upstream elements at -40 to -60 position
E) Any mutation on the upstream of a gene will definitely have deleterious effect on gene transcription.

Question

Quizplus · Accepted Answer

The region between -10 and -35 consensus sequences is not essential for transcription initiation and mutations in this region are less likely to affect transcription.

Mutations in Which of the Following Regions Upstream of the RNA