What may be the consequence of a mutation in the gene that encodes eukaryotic Rat1 exonuclease for eukaryotic transcription mediated by RNA polymerase II?
A) The transcription may end prematurely, resulting in shorter mRNA transcript.
B) The transcription may not be properly terminated, and RNA polymerase II may not be released.
C) The transcription may be delayed indefinitely, which may kill the cell.
D) The RNA transcript may not be able to dissociate from the DNA template.
E) The transcription may not terminate and result in much longer RNA.

Question

Quizplus · Accepted Answer

Rat1 exonuclease is involved in the termination of transcription by degrading the RNA downstream of the cleavage site, facilitating the release of RNA polymerase II. A mutation could impair this process, preventing proper termination.

What May Be the Consequence of a Mutation in the Gene