Some of the body's cells get very low levels of lymphocyte traffic and the body's lymphocytes rarely encounter the unique antigens in those body sites. Thus, if lymphocytes are suddenly exposed to those antigens, they may initiate an immune response against those cells. Which theory of autoimmunity is this?

Question

Quizplus · Accepted Answer

The sequestered antigen theory suggests that certain antigens are normally hidden from the immune system. If these antigens are exposed due to injury or other reasons, the immune system may recognize them as foreign and initiate an immune response, potentially leading to autoimmunity.

Some of the Body's Cells Get Very Low Levels of Lymphocyte