A 25- year- old female was evaluated for episodes of numbness and difficulty in moving her extremi She is currently asymptomatic. Laboratory results were as follows. What is the most likely diagnosis?

Complete blood count (CBC)—within normal limits
Urinalysis—within normal limits
Renal function tests (BUN and creatinine)—within normal limits
Electrolytes and glucose—within normal limits
Antinuclear antibody (ANA)—negative
Antiacetylcholine receptor antibody—negative
Total protein, total IgG and myelin basic protein in cerebrospinal fluid (CSF)—elevated
High resolution protein electrophoresis of serum—polyclonal gamma region
High resolution protein electrophoresis of CSF—oligoclonal gamma region

Question

A 25- year- old female was evaluated for episodes of numbness and difficulty in moving her extremi She is currently asymptomatic. Laboratory results were as follows. What is the most likely  diagnosis?

Complete blood count (CBC)—within normal limits
Urinalysis—within normal limits
Renal function tests (BUN and creatinine)—within normal limits
Electrolytes and glucose—within normal limits
Antinuclear antibody (ANA)—negative
Antiacetylcholine receptor antibody—negative
Total protein, total IgG and myelin basic protein in cerebrospinal fluid (CSF)—elevated
High resolution protein electrophoresis of serum—polyclonal gamma region
High resolution protein electrophoresis of CSF—oligoclonal gamma region

Quizplus · Accepted Answer

The elevated myelin basic protein in cerebrospinal fluid (CSF) and the presence of oligoclonal bands in the CSF are indicative of multiple sclerosis (MS), a condition characterized by episodes of neurological symptoms such as numbness and difficulty moving extremities.

A 25- Year- Old Female Was Evaluated for Episodes of Numbness