Each immunodeficiency syndrome below is paired correctly with its underlying defect except
A) CD3 complex deficiency/no CD3 complex and therefore no T cells.
B) X- linked hyper- IgM/defect in T helper cell CD154 which is required to stimulate B cell CD40 for immunoglobulin class switching.
C) bare lymphocyte syndrome/no CD4 and CD8 complex and therefore no T cells.
D) Wiscott- Aldrich syndrome/defect in production of Wiscott- Aldrich protein necessary for lymphocytes to change cytoskeletal structure and respond to stimuli.
E) Bruton's X linked agammaglobulinemia/deficient B cell tyrosine kinase, arrested B cell maturation, and no circulating mature B cells.
Correct Answer:
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