Most nucleic acid amplification techniques amplify and detect target DNA, but in branched chain detection a labeled probe attaches to the target DNA and the label is amplified for detection.

Question

Quizplus · Accepted Answer

In branched DNA (bDNA) assays, the target DNA is detected by hybridization to a specific probe, and instead of amplifying the target DNA, multiple labeled probes are used to amplify the signal, making it a unique method among nucleic acid amplification techniques.

Most Nucleic Acid Amplification Techniques Amplify and Detect Target DNA