Early observations of a cultured cell line indicated that the cells did not exhibit either density-dependent inhibition or anchorage dependence. What do these observations suggest about this cell line?
A) The cells are unable to form spindle microtubules.
B) The cells follow an altered series of cell cycle phases.
C) The cells show characteristics of tumors.
D) The cells have nonfunctional MPF.

Question

Quizplus · Accepted Answer

Density-dependent inhibition and anchorage dependence are both mechanisms that prevent uncontrolled cell growth and are characteristics of normal, non-tumorigenic cells. The absence of both these mechanisms suggests that the cell line has lost some of its regulation of cell growth, which are hallmarks of cancerous or tumor cells.

Early Observations of a Cultured Cell Line Indicated That the Cells