Why might using retroviral vectors for gene therapy increase the patient's risk of developing cancer?
A) Retroviral vectors may introduce proteins from the virus.
B) Retroviral vectors do not express the genes that were introduced into a patient's cells.
C) Retroviral vectors do not integrate their recombinant DNA into the patient's genome.
D) Retroviral vectors integrate recombinant DNA into the genome in ways that may misregulate the expression of genes at or near the site of integration.

Question

Quizplus · Accepted Answer

Retroviral vectors have the ability to integrate recombinant DNA into the genome, which may affect the expression of genes at or near the site of integration. This can lead to the misregulation of genes, including those that are involved in cell growth and division, potentially increasing the risk of cancer development.

Why Might Using Retroviral Vectors for Gene Therapy Increase the Patient's