Yeast research with autonomously replicating sequences (ARSs),along with digestion of chromatin with DNase I,have led scientists to determine that
A) DNA is not protected inside a nucleosome.
B) ARSs are really plasmids.
C) RSs bond irreversibly to replication enzymes.
D) origins of replication are accessible regions of DNA devoid of nucleosomes.
E) ARSs replicate without DNA polymerase.

Question

Quizplus · Accepted Answer

Yeast research with autonomously replicating sequences (ARSs) and digestion of chromatin with DNase I have led scientists to determine that origins of replication are accessible regions of DNA devoid of nucleosomes. This means that the DNA must be in an open chromatin conformation for replication to occur.

Yeast Research with Autonomously Replicating Sequences (ARSs),along with Digestion of Chromatin