Question 1

What is an enhanceosome?

Accepted Answer

The answer of What is an enhanceosome?...

Question 2

Why is genomic imprinting considered an epigenetic alteration?

Accepted Answer

The answer of Why is genomic imprinting considered an epigenetic...

Question 3

Gene expression can be modulated posttranscriptionally through micro RNAs (miRNAs)in eukaryotes.

Accepted Answer

Micro RNAs (miRNAs) can regulate gene expression posttranscriptionally by binding to target mRNAs and inhibiting their translation or promoting their degradation.

Question 4

You have cloned and sequenced a new mouse gene and wish to know whether chromatin structure may affect its transcription.You DNase treat and then run Southern analysis.In the mouse strain with hypothetical phenotype A you detect your gene,but it is not detected in DNase treated samples from the mouse strain with phenotype B.What do you suspect as the cause?

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The answer of You have cloned and sequenced a new...

Question 5

Unlike prokaryotes,eukaryotes have three RNA polymerases.What are they and what does each do?

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The answer of Unlike prokaryotes,eukaryotes have three RNA polymerases.What are...

Question 6

Reporter constructs are used to identify and characterize DNA sequences that regulate the expression levels of specific genes.What two DNA sequences are linked together to generate a reporter construct?

Accepted Answer

The answer of Reporter constructs are used to identify and...

Question 7

RNA interference is a posttranscriptional process for modulating gene expression in prokaryotes.

Accepted Answer

RNA interference is a posttranscriptional process for modulating gene expression in eukaryotes, not prokaryotes.

Question 8

You are studying a brain region-specific mouse gene.You have cloned and sequenced the gene but wish to identify the DNA sequences that direct the regional specificity.Describe an experimental technique that would allow you to test this.

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Question 9

All somatic cells in an individual have the same genetic content.Yet different cell types have different functions.What allows two cells with identical DNA content to function differently?

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The answer of All somatic cells in an individual have...

Question 10

Describe two modes of action by which RNA interference can modulate gene expression.

Accepted Answer

The answer of Describe two modes of action by which...

Question 11

How does chromatin structure regulate gene transcription?

Accepted Answer

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Question 12

Gene A is maternally imprinted while Gene B is paternally imprinted.A mother with Genes A and B imprinted and a father with an imprinted Gene A have a daughter and a son.The children then marry individuals known not to be imprinted for either gene.What is the imprint status of the daughter and son respectively? If each marriage results in the birth of a daughter and a son,what would you expect the imprint status of genes A and B to be for the grandchildren?

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Question 13

Each eukaryotic class II gene contains two kinds of essential DNA sequences.What are they?

Accepted Answer

The answer of Each eukaryotic class II gene contains two...

Quiz 10: Analyzing Genomic Variation