Which Facts About Enzymes Are Not Visualized in This Figure

Which facts about enzymes are not visualized in this figure?

A) Enzymes stabilize the transition state of the reaction-that point where the reactants are becoming the products.
B) A cofactor is often required for enzyme activity.
C) Enzymes are not consumed or permanently changed in a reaction.
D) A substrate binds to an enzyme at the active site as described by the "induced- fit" model
E) Specific products are generated.