Question 1

The biggest problem with tyramine intolerance is

Accepted Answer

NE release and its consequences

Question 2

Which of the following is not a mechanism of action for psychotropic medications?

Accepted Answer

Psychotropic medications work by affecting neurotransmitter systems, either by altering the release, reuptake, or degradation of neurotransmitters, or by modulating receptor activity. They do not create new functions in cells, which distinguishes option D as the correct answer.

Question 3

The key mechanism of action in all families of benzodiazepines is

Accepted Answer

Benzodiazepines work by enhancing the effect of the neurotransmitter GABA (gamma-aminobutyric acid), which is an inhibitory neurotransmitter in the brain, thus they act as GABA agonists, not by directly activating GABA receptors, but by increasing the GABAergic activity.

Question 4

When enzymes that are responsible for drug metabolism increase in response to the consistent presence of the drug, we call that

Accepted Answer

metabolic tolerance

Question 5

In your drawing in part I, the antidepressant sertraline would likely

Accepted Answer

Sertraline is a selective serotonin reuptake inhibitor (SSRI) that works by inhibiting the serotonin transporter (SERT), which is responsible for the reuptake of serotonin (5-HT) from the synaptic cleft back into the presynaptic neuron. This increases the concentration of serotonin in the synaptic cleft, enhancing serotonergic neurotransmission.

Question 6

An example of cross tolerance is the relationship between

Accepted Answer

Benzodiazepines and alcohol

Question 7

The primary mechanism of therapeutic action for Abilify is

Accepted Answer

Abilify (aripiprazole) is known for its unique mechanism of action among antipsychotics, which is not fully understood. It is thought to act as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors, but the exact mechanism contributing to its therapeutic effects remains somewhat unclear.

Question 8

A loading dose refers to

Accepted Answer

an initial dose that is higher than subsequent doses

Question 9

The best benzodiazepine for elderly patients would be one less reliant on the liver for metabolizing like

Accepted Answer

oxazepam

Question 10

In your drawing from part 1, a synaptic cleft is

Accepted Answer

a physical gap across which neurotransmitters diffuse

Question 11

Which of the following is not a vegetative symptom of depression?

Accepted Answer

low self-esteem

Question 12

Stimulating an autoreceptor will

Accepted Answer

The answer of Stimulating an autoreceptor will
...

Question 13

The black box warning on SSRI antidepressants means

Accepted Answer

these medications should only be given under special circumstances

Question 14

A specialized chemical messenger that carries information from one neuron to another at the synapse is good definition of

Accepted Answer

a neurotransmitter molecule

Question 15

Although Olanzapine is known as a new-generation anti-psychotic, it may also be used as

Accepted Answer

An anti-manic agent

Question 16

The second messenger systems sequence of events moves in which order?

Accepted Answer

The correct sequence is: First messenger binds to the receptor, which activates the G-protein, and then the enzyme is activated to produce the second messenger.

Question 17

The efficacy of Buspirone for anxiety is

Accepted Answer

Buspirone has an efficacy rate of approximately 55% for treating anxiety, which is generally lower than some antidepressants and benzodiazepines like alprazolam.

Question 18

The blood-brain barrier

Accepted Answer

is a lipophilicitious membrane psychotropic meds must pass through

Question 19

Advocating for clients

Accepted Answer

is particularly important with children

Question 20

Of two families of benzodiazepine receptors

Accepted Answer

Only one needs to be targeted to create a hypnotic

Quiz 2: Psychopharmacology for Mental Health, Part B