“Calcium-induced calcium release” refers to A) Increased I_ca upon beta adrenergic stimulation B) Release of Ca from the cardiac SR by Ca that enters the cell across the T-tubule C) Relaxation of cardiac muscle when Ca is removed by the SR SERCA2a pump D) Increased Ca uptake by SR following contraction E) Both A and C are correct

Question

Quizplus · Accepted Answer

"Calcium-induced calcium release" specifically refers to the mechanism where calcium entering the cell through the L-type calcium channels (located on the T-tubules) triggers the release of additional calcium from the sarcoplasmic reticulum (SR) into the cytoplasm in cardiac muscle cells. This process is crucial for cardiac muscle contraction.

“Calcium-Induced Calcium Release” Refers to