At very high flow rates, the concentration of a diffusable metabolite in the ISF A) Goes to zero B) Approaches the arteriolar concentration of the metabolite C) Approaches the cytosolic concentration of the m etabolite D) Approaches a fraction (1-E) of the arteriolar concentration E) Approaches the rate of metabolism of the metabolite, Q_M, divided by E

Question

Quizplus · Accepted Answer

At very high flow rates, the concentration of a diffusable metabolite in the interstitial fluid (ISF) approaches the arteriolar concentration of the metabolite. This is because the high flow rate reduces the time available for the metabolite to diffuse out of the blood, leading to an equilibrium where the ISF concentration mirrors that of the arteriole.

At Very High Flow Rates, the Concentration of a Diffusable