Benzer's analysis of phage genomes included deletion mapping. Since recombination could not occur in the area of a deletion, an infection by two phage strains, one of which has a deletion and the other a point mutation, that results in no wild- type recombinants being produced indicates_________ .
A) that the deletion includes the position of the point mutation in a different gene
B) the distance between the two types of mutation
C) that the point mutation is recessive
D) that the deletion includes the position of the point mutation in the same gene
E) that the point mutation is dominant

Question

Quizplus · Accepted Answer

Benzer's deletion mapping technique relies on the principle that recombination cannot occur in regions where one of the phages has a deletion. If no wild-type recombinants are produced when a phage with a deletion is crossed with a phage with a point mutation, it indicates that the deletion encompasses the site of the point mutation within the same gene, preventing any recombination that could restore the wild-type phenotype.

Benzer's Analysis of Phage Genomes Included Deletion Mapping