Once a chromosomal position for a putative gene associated with Parkinson disease is verified, which of the following is a next step?
A) ascertaining all living and at- risk individuals who are family members of the affected test subjects
B) fine mapping of the linkage region to identify particular variants for influencing risk
C) developing a FISH screening test to identify pre- Parkinson patients
D) determining whether this locus is mutated in all Parkinson patients
E) using a genome- wide linkage SNP panel to identify more minor genes

Question

Quizplus · Accepted Answer

Fine mapping of the linkage region is a crucial next step after verifying a chromosomal position for a gene associated with a disease like Parkinson's. This process helps to identify specific variants within the region that may influence the risk of developing the disease.

Once a Chromosomal Position for a Putative Gene Associated with Parkinson