Question 1

Each year, large parts of Australia fall within the sizable hole in the Earth's ozone layer that forms over the Antarctic, a situation that is likely linked to the high skin cancer rate found in that country. The protective motto in many parts of Australia is "slip, slap, slop"-slip on a shirt, slap on a hat, and slop on sunscreen. At the molecular level, what exactly are the mutagenic effects of UVA and UVB radiation?

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Question 2

Suppose you are studying a rare spontaneous cancer in cats, which you suspect is retrovirus-induced. What kinds of retroviral insertion could lead to cancer, and what kind of genetic signature would you look for to distinguish between them?

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Question 3

What is metastasis, and why is metastatic cancer the most difficult cancer to treat?

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Question 4

What kinds of cancers might someday be treated with iRNAs, which you learned about in Chapters 20 and 21?

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Quiz 23: DNA Replication

Suppose you are studying a rare spontaneous cancer in cats, which you suspect is retrovirus-induced. What kinds of retroviral insertion could lead to cancer, and what kind of genetic signature would you look for to distinguish between them?

What is metastasis, and why is metastatic cancer the most difficult cancer to treat?

What kinds of cancers might someday be treated with iRNAs, which you learned about in Chapters 20 and 21?