While caring for a client receiving Ultram (tramadol) for moderate pain control, the nurse recognizes increased CNS depression can occur if this medication is given concurrently with which of the following? Select all that apply.
A) Antineoplastic agents
B) Antihistamines
C) Opioid analgesics
D) Anticoagulants
E) Sedative/hypnotics
F) Bisphosphonates

Question

Quizplus · Accepted Answer

Concurrent use of Ultram with antihistamines, opioid analgesics, and sedative/hypnotics can increase CNS depression due to additive pharmacological effects. Antineoplastic agents, anticoagulants, and bisphosphonates do not have a significant interaction with Ultram.

While Caring for a Client Receiving Ultram (Tramadol) for Moderate