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You Study Two Cell Lines

Question 28

Multiple Choice

You study two cell lines. In one, the MDM2 protein is overexpressed; in the other the p53 protein is absent. What difference would you expect in the behavior of these two cell lines?


A) In cells containing overexpressed MDM2, p53 levels will be low; in cells lacking the p53 protein, p53 levels are also low; thus there will be no difference in behavior.
B) In cells containing overexpressed MDM2, p53 levels will be high; in cells lacking the p53 protein, p53 levels are low; thus there will be a drastic difference in behavior.
C) In cells containing overexpressed MDM2, p53 levels will be high; in cells lacking the p53 protein, p53 levels are high; thus there will be no difference.
D) In cells containing overexpressed MDM2, p53 levels will be low; in cells lacking the p53 protein, p53 levels are high; thus there will be no difference in behavior.
E) None of these are correct.

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