What is this difference between si/miRNAs and piRNAs?
A) piRNAs are longer than si/miRNAs.
B) The majority of mammalian piRNAs can be mapped to a small number of huge genomic loci, unlike si/mi RNAs.
C) The formation of piRNAs does not involve the formation of dsRNA precursors, unlike si/mi RNAs.
D) Formation of piRNAs does not involve cleavage by Dicer ribonuclease, but instead it depends on the endonuclease activity of the PIWI protein acting on a long, single stranded primary transcript.
E) All of these are correct.
Correct Answer:
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