You are working on a project in which you block autophagy in a particular portion of the brain of a laboratory animal. What happens to these animals? (Select all correct choices)
A)Nothing happens since nerve cells are so long-lived.
B)That region of the nervous system experiences a massive loss of nerve cells.
C)There is slight, but not dangerous damage, to the organelles and proteins of the nerve cells.
D)There is continuous damage to the proteins and organelles of these long-lived cells.

Question

Quizplus · Accepted Answer

Autophagy is the process by which cells break down and recycle their own components, including organelles and proteins. Blocking autophagy in nerve cells can lead to accumulation of damaged organelles and proteins, causing continuous damage to the cells. Over time, this can lead to a massive loss of nerve cells in the targeted region of the brain. Therefore, choices B and D are correct, while choices A and C are incorrect.

You Are Working on a Project in Which You Block