Epidermolysis bullosa, an inherited blistering disease, is caused by ________.
A)production of antibodies against hemidesmosome plaque proteins
B)production of autoantibodies
C)production of antibodies against spot desmosome plaque proteins
D)genetic alterations in any one of a number of hemidesmosomal proteins
E)production of antibodies against connexins

Question

Quizplus · Accepted Answer

Epidermolysis bullosa is caused by genetic alterations in any one of a number of hemidesmosomal proteins, which are responsible for anchoring the epidermis to the underlying dermis. This results in fragile skin that is prone to blistering and tearing. Antibodies do not play a direct role in the development of this disease.

Epidermolysis Bullosa, an Inherited Blistering Disease, Is Caused by ________