You genetically engineer nonadhesive cells to express different varieties of cadherins and then mix the cells in various combinations. What is the best prediction of the outcome?
A)The genetically engineered cells adhere preferentially to cells expressing one of the other cadherins.
B)The genetically engineered cells adhere preferentially to cells expressing the same cadherins.
C)The genetically engineered cells do not stick to any other cells.
D)The genetically engineered cells die.
E)The genetically engineered cells migrate to a different location.

Question

Quizplus · Accepted Answer

Cadherins are cell-adhesion molecules that bind to other cadherins of the same type in order to form strong cell-cell adhesion. Therefore, it is predicted that the genetically engineered cells expressing a certain type of cadherin will adhere preferentially to other cells expressing the same type of cadherin, thus forming clusters of cells with similar cadherin expression.

You Genetically Engineer Nonadhesive Cells to Express Different Varieties of Cadherins