Which region of the brain has been shown to suffer an increased mutation rate in patients with Parkinson's disease, according to some studies?

Question

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Some studies have shown that the substantia nigra, a region in the midbrain that is responsible for producing dopamine, suffers an increased mutation rate in patients with Parkinson's disease. This mutation rate leads to the death of dopamine-producing neurons and the onset of Parkinson's symptoms.

Which Region of the Brain Has Been Shown to Suffer