Integral membrane proteins have been engineered to lack the portion that normally projects into the extracellular space. When the gene is inserted in cells, what happens to the mobility of this protein in the membrane?
A)It moves at a much faster rate than the wild type protein.
B)It moves at a much slower rate than the intact protein.
C)It does not move at all.
D)It is not inserted into the membrane so nothing can be learned about their mobility.
E)It flips to the opposite leaflet.

Question

Quizplus · Accepted Answer

Integral membrane proteins that lack the portion projecting into the extracellular space can move more freely within the membrane because they are not anchored or restricted by interactions with extracellular components, leading to a faster mobility rate compared to the wild type protein.

Integral Membrane Proteins Have Been Engineered to Lack the Portion