You isolate the enzyme that synthesizes folic acid in bacteria and conduct some enzyme kinetics experiments. You find, not surprisingly, that sulfa drugs inhibit the enzyme's activity. What happens to the Vmax and KM of this enzyme when it is treated with sulfa drugs? (Select all the correct statements relating to this experiment)
A) sulfa drugs are competitive inhibitors of the folic acid synthesis pathway
B) Vmax will stay the same and KM of this enzyme will decrease
C) Vmax will decrease and KM of this enzyme will stay the same
D) Vmax will increase and KM of this enzyme will increase
E) Vmax will stay the same and KM of this enzyme will increase
Correct Answer:
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