How might an amino acid change at a site distant from the active site of the enzyme alter the enzyme's substrate specificity?
A) by changing the enzyme's stability
B) by changing the enzyme's location in the cell
C) by changing the shape of the protein
D) by changing the enzyme's pH optimum
E) an amino acid change away from the active site cannot alter the enzyme's substrate specificity

Question

Quizplus · Accepted Answer

Amino acid changes can have a significant impact on the three-dimensional structure of the protein. A change in the shape of the protein can alter the way it interacts with its substrate, potentially leading to a change in substrate specificity. While changes in stability, location, and pH optimum could potentially impact the enzyme's function, they are less likely to directly affect substrate specificity. Answer E is incorrect as changes in protein structure can have significant effects on enzyme function, even if they occur away from the active site.

How Might an Amino Acid Change at a Site Distant