Since steroid receptors are located intracellularly, which of the following is true?
A) The receptor molecules are themselves lipids or glycolipids.
B) The steroid/receptor complex can cross the nuclear membrane.
C) The unbound steroid receptors are quickly recycled by lysosomes.
D) The concentration of steroid receptors must be relatively high in most cells.
E) The receptor molecules are free to move in and out of most organelles.

Question

Quizplus · Accepted Answer

Steroid receptors are located intracellularly, specifically in the cytoplasm or nucleus. Since steroid molecules are hydrophobic, they can easily cross the plasma membrane and bind to their corresponding receptors in the cytoplasm or nucleus. Once the steroid binds to its receptor, the steroid/receptor complex can then cross the nuclear membrane to bind to specific regions of DNA and initiate gene transcription.

Since Steroid Receptors Are Located Intracellularly, Which of the Following