An experimenter has altered the 3' end of the tRNA corresponding to the amino acid methionine in such a way as to remove the 3' AC. Which of the following hypotheses describes the most likely result?
A) tRNA will not form a cloverleaf.
B) The nearby stem end will pair improperly.
C) The amino acid methionine will not bind.
D) The anticodon will not bind with the mRNA codon.
E) The aminoacylsynthetase will not be formed.

Question

Quizplus · Accepted Answer

The 3' AC of tRNA is where the amino acid attaches during the process of translation. Thus, the removal of this sequence would prevent methionine from binding to the tRNA, and therefore, option C is the most likely result. Option A is incorrect because even if the 3' AC is removed, the tRNA can still form the cloverleaf structure. Option B is incorrect because the stem-loop pairing occurs in the regions other than the 3' end. Option D is incorrect because it involves the binding of the anticodon region to the mRNA codon, which is not directly affected by the 3' end alteration. Option E is not relevant to the altered tRNA molecule itself.

An Experimenter Has Altered the 3' End of the TRNA