Which of the following sequences in double-stranded DNA is most likely to be recognized as a cutting site for a restriction enzyme?
A) AAGG
TTCC
B) AGTC
TCAG
C) GGCC
CCGG
D) ACCA
TGGT
E) AAAA
TTTT

Question

Quizplus · Accepted Answer

Restriction enzymes typically recognize palindromic sequences, meaning the sequence reads the same on both strands when read in the same 5' to 3' direction. The sequence in option C (GGCC and CCGG) is a palindromic sequence and is therefore the most likely to be recognized as a cutting site for a restriction enzyme. Option A has a palindrome, but it is not in the correct reading orientation. Option B and option D are not palindromic sequences. Option E has no repeated sequence.

Which of the Following Sequences in Double-Stranded DNA Is Most