Liver is the essential organ for regulation of glucose levels in blood through storage, release and production of "new" glucose from non-carbohydrate substrates. What type of receptors do hepatocytes express to fulfill this role?
A) glucagon receptors only, no insulin receptors
B) insulin receptors only, no glucagon receptors
C) both insulin and glucagon receptors
D) GLUT 4 receptors only

Question

Quizplus · Accepted Answer

Hepatocytes express both insulin and glucagon receptors to regulate glucose levels in blood. Insulin stimulates the storage of glucose in the liver, while glucagon promotes the release of glucose into the blood. Therefore, both receptors are necessary for the liver to maintain glucose homeostasis. GLUT 4 receptors are present on skeletal muscle and adipose tissue to facilitate glucose uptake, but not on hepatocytes.

Liver Is the Essential Organ for Regulation of Glucose Levels