The phenomenon of occurs when repeated administration of a drug results in reduced response to that drug.

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Tolerance is the phenomenon where repeated exposure to a drug results in a reduced effect of the drug. This requires an increased dosage of the drug to achieve the same effect as before. Dependence refers to the body's adaptation to the presence of a substance, which leads to physical and emotional symptoms of withdrawal when the substance is removed. Conditioning refers to a type of learning where a neutral stimulus becomes associated with another stimulus to elicit a particular response. Withdrawal refers to the onset of symptoms when a person stops taking a drug after becoming physically and/or psychologically dependent on it.

The Phenomenon of Occurs When Repeated Administration of a Drug