Modification enzymes typically methylate specific bases within the recognition sequence to prevent digestion of the nucleotide sequence by restriction endonucleases.

Question

Quizplus · Accepted Answer

This is true. Modification enzymes add a methyl group to a specific base within the recognition sequence of the DNA, which prevents restriction endonucleases from recognizing and cutting the sequence.

Modification Enzymes Typically Methylate Specific Bases Within the Recognition Sequence