When Microbes Are Introduced into Normally Sterile Body Sites, or When

When microbes are introduced into normally sterile body sites, or when tissues are damaged, inflammation occurs. The purpose of this is to contain a site of damage, localize the response, eliminate the invader, and restore tissue function. Select the correct sequence of events for an inflammation response.
1) The phagocytes then produce other adhesion molecules that strengthen their attachment to the endothelial cells.
2) Tight junctions between endothelial cells are disrupted, allowing leakage from the vessels into the tissue.
3) Endothelial cells of the blood vessels produce adhesion molecules that loosely "grab" phagocytic cells.
4) In response to various chemoattractants, the phagocytes leave the blood vessels and move into the surrounding tissues.
5) The diameter of local blood vessels increases due to the action of inflammatory mediators, slowing blood flow in the area.

A) 1, 2, 3, 4, 5
B) 5, 2, 3, 1, 4
C) 3, 2, 4, 1, 5
D) 1, 3, 5, 2, 4
E) 4, 5, 1, 2, 3