Given the name "leukocyte adhesion deficiency," which of the following steps in the inflammation process given below do you think is/are not carried out in a person with this condition?
1) Tight junctions between endothelial cells are disrupted, allowing fluid to leak from the vessels into the tissue.
2) The phagocytes bind to the endothelial cells and exit the blood vessel by a process called diapedesis.
3) Once in the tissues, phagocytic cells engulf and destroy any microbial invaders.
4) The increase of fluids in the tissues causes the swelling and pain associated with inflammation.
5) The diameter of local blood vessels increases due to the action of inflammatory mediators.
A) 1
B) 2
C) 3
D) 1 and 2
E) 2, 3, and 5

Question

Given the name "leukocyte adhesion deficiency," which of the following steps in the inflammation process given below do you think is/are not carried out in a person with this condition?
1) Tight junctions between endothelial cells are disrupted, allowing fluid to leak from the vessels into the tissue.
2) The phagocytes bind to the endothelial cells and exit the blood vessel by a process called diapedesis.
3) Once in the tissues, phagocytic cells engulf and destroy any microbial invaders.
4) The increase of fluids in the tissues causes the swelling and pain associated with inflammation.
5) The diameter of local blood vessels increases due to the action of inflammatory mediators.
A) 1
B) 2
C) 3
D) 1 and 2
E) 2, 3, and 5

Quizplus · Accepted Answer

In a person with leukocyte adhesion deficiency, phagocytes are unable to bind to endothelial cells and exit the blood vessel by diapedesis. Therefore, step 2 is not carried out.

Given the Name "Leukocyte Adhesion Deficiency," Which of the Following