Your Father Has Just Been Diagnosed with Rheumatoid Arthritis

Your father has just been diagnosed with rheumatoid arthritis. He has pain and the sensation of "pins and needles" in some if his finger joints and also in his wrists. He knows you covered autoimmune diseases in your microbiology class, so asks you to help him understand his condition.
-In an effort to help your father understand his symptoms, you tell him that RA 

A) is a localized disease, affecting only a single joint, usually the left knee.
B) occurs when B cells infiltrate the joints and, when stimulated by specific antigens, release cytokines that cause inflammation.
C) is one of the most rarest autoimmune diseases, and unlike arthritis that arises from wear and tear of joints, only occurs later in life.
D) is characterized by joint damage that results when antibodies to tissue in the joints form immune complexes characteristic of type III hypersensitivity.
E) is a condition in which cells called cytotoxic T cells release antibodies that target connective tissues, most often within joints.