Your Father Has Just Been Diagnosed with Rheumatoid Arthritis

Your father has just been diagnosed with rheumatoid arthritis. He has pain and the sensation of "pins and needles" in some if his finger joints and also in his wrists. He knows you covered autoimmune diseases in your microbiology class, so asks you to help him understand his condition.
-You discuss treatment approaches that are taken for various autoimmune diseases. Which of the following is NOT a reasonable option for treating autoimmunity?

A) Limiting the immune response with anti-inflammatory or immunosuppressant medications.
B) Replacement therapy to restore damaged tissues or tissue products, for example giving insulin to diabetics.
C) Gene therapy, using retroviruses to replace defective genes coding for enzymes involved in recognizing "self" antigens.
D) Inducing tolerance by introducing the antigen by the oral route, so that the immune system "learns" to tolerate it.
E) These are all reasonable approaches to treating autoimmunity.