Questions Refer to the Map and Image Below

Questions refer to the map and image below.
Commercial Hubs in Mesoamerica and North America c. 1000 Monks Mound, Cahokia Mounds State Historic Site
-Which of the following is an accurate interpretation of the information in the map above?

A) Overland trade routes predominated in the Mississippian culture.
B) Toltec cities traded only with Mayan cities.
C) Most of the major cities arose in Mesoamerica.
D) Most major cities arose close to navigable waterways.